Anti-CLAC-P (NC3 region) Antibody

Our CLAC-P (NC3 region) rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human and mouse CLAC-P (NC3 region) and is antigen affinity purified. It is great for use in WB.

Product Specifications

Background

Antibodies against senile plaque (SP) amyloid obtained a clone 9D2, which labeled amyloid fibrils in SPs and reacted with approximately 50/100 kDa polypeptides in Alzheimer's disease (AD) brains. The 9D2 antigen was identified as CLAC (collagen-like Alzheimer amyloid plaque component), and its precursor as CLAC-P/collagen type XXV. Both secreted and membrane-tethered forms of CLAC-P/collagen type XXV specifically bound to fibrillized Abeta, implicating these proteins in beta-amyloidogenesis and neuronal degeneration in AD

Synonyms

COL25A1, Collagen alpha-1 XXV chain, Alzheimer disease amyloid-associated protein, AMY, Collagen-like Alzheimer amyloid plaque component

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

COL25A1

UniProt

Q9BXS0

Host

Rabbit

Reactivity

Human and Mouse

Immunogen

Synthetic peptide corresponding to amino acids from the NC23 region of human CLAC-P

Immunogen Type

Human

Target

CLAC-P (NC3 region)

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

Format

Antigen Affinity Purified

Form

Liquid

Buffer

PBS + 0.02% NaN3

Shipping Conditions

Blue Ice

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.