Anti-TRAIL R3 Antibody
Our TRAIL R3 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human TRAIL R3 and is antigen affinity purified. It is great for use in WB.
Product Specifications
Background
DcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis.
Synonyms
TNFRSF10C, DCR1, LIT, TRAILR3, TRID, UNQ321/PRO366
Other Statements
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
Gene Name
TNFRSF10C
UniProt
O14798
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide corresponding to amino acids from the N-terminal region of human TRAIL R3 protein
Immunogen Type
Human
Target
TRAIL R3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Format
Antigen Affinity Purified
Form
Liquid
Buffer
PBS + 0.02% NaN3
Shipping Conditions
Blue Ice
Storage Conditions
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
WB Dilution
1:500-1:1000
Specificity
Reacts with the N terminus of the mature human TRAIL-R3 protein
Formulation
Prepared from pooled rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.
Quality Control
Western blots performed on each lot.
Isotype
IgG
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