Anti-TRAIL R3 Antibody

Our TRAIL R3 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human TRAIL R3 and is antigen affinity purified. It is great for use in WB.

Product Specifications

Background

DcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis.

Synonyms

TNFRSF10C, DCR1, LIT, TRAILR3, TRID, UNQ321/PRO366

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

TNFRSF10C

UniProt

O14798

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide corresponding to amino acids from the N-terminal region of human TRAIL R3 protein

Immunogen Type

Human

Target

TRAIL R3

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

Format

Antigen Affinity Purified

Form

Liquid

Buffer

PBS + 0.02% NaN3

Shipping Conditions

Blue Ice

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.