Anti-HDAC10 Antibody
Our HDAC10 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human HDAC10 and is antigen affinity purified. It is great for use in WB.
Product Specifications
Background
A novel class II histone deacetylase, HDAC10 is most similar to HDAC6. Both contain a unique, putative second catalytic domain not found in other HDACs. In HDAC10, however, this domain is not functional. Unlike HDAC6, which is normally a cytoplasmic deacetylase, HDAC10 resides in both the nucleus and cytoplasm. Data suggests that HDAC10 may play roles both in the nucleus, as a transcriptional modulator, and in the cytoplasm in an unidentified role. HDAC10 variants seem present in certain cell lines and tissues that are as of yet not characterized.
Synonyms
Histone deacetylase 10, HD10
Other Statements
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
Gene Name
HDAC10
UniProt
Q969S8
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human HDAC 10 protein
Immunogen Type
Human
Target
HDAC10
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Format
Antigen Affinity Purified
Form
Liquid
Buffer
PBS + 0.02% NaN3
Shipping Conditions
Blue Ice
Storage Conditions
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
WB Dilution
1:500-1:1000
Specificity
Reacts with human HDAC10 protein.
Formulation
Prepared from pooled rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.
Quality Control
Western blots performed on each lot.
Isotype
IgG
Curated Selection
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