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Anti-PAR4 Antibody

Our PAR4 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human PAR4 and is antigen affinity purified. It is great for use in WB.

Product Specifications

Background

The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms' tumor. Par-4 (for prostate apoptosis response) is a WT1-interacting protein that also functions as a transcriptional repressor. Par-4 contains a putative leucine zipper domain and is specifically upregulated during apoptosis of prostate cells.

Synonyms

PAWR, PRKC Apoptosis WT1 Regulator, Prostate apoptosis response 4 protein, Transcriptional repressor PAR4, WT1 Interacting Protein

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

PAWR

UniProt

Q96IZ0

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide corresponding to amino acids from the N-terminal region of human PAR4 protein

Immunogen Type

Human

Target

PAR4

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Format

Antigen Affinity Purified

Form

Liquid

Buffer

PBS + 0.02% NaN3

Shipping Conditions

Blue Ice

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

WB Dilution

1:500-1:1000

Specificity

Reacts with the N-terminal region of human PAR4 protein

Formulation

Prepared from pooled rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.

Quality Control

Western blots performed on each lot.

Isotype

IgG

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