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Anti-BRAF35 Antibody

Our BRAF35 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human BRAF35 and is antigen affinity purified. It is great for use in WB.

Product Specifications

Background

Mutations of the human BRCA2 gene confer susceptibility to breast cancer. A structural DNA binding component has been identified and is designated as BRCA2-Associated Factor 35 (BRAF35) . There is a close association of the BRAF35/BRCA2 complex with condensed chromatin coincident with histone H3 phosphorylation. Experimental evidence suggests a role for the BRCA2/BRAF35 complex in the modulation of cell cycle progression.

Synonyms

HMG20B, BRCA2 associated factor 35, BRAF25, High Mobility Group Protein 20B, HMG box containing protein 20B, SMARCE1-related protein, Sox like transcriptional factor

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

HMG20B

UniProt

Q9P0W2

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide corresponding to amino acids from the N-terminal region of human BRAF35 protein

Immunogen Type

Human

Target

BRAF35

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Format

Antigen Affinity Purified

Form

Liquid

Buffer

PBS + 0.02% NaN3

Shipping Conditions

Blue Ice

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

WB Dilution

1:500-1:1000

Specificity

Reacts with the N-terminal region of human BRAF35 protein

Formulation

Prepared from pooled rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.

Quality Control

Western blots performed on each lot.

Isotype

IgG

Curated Selection

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