Anti-IKAP (C-terminal) Antibody

Our IKAP rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human IKAP and is antigen affinity purified. It is great for use in WB.

Product Specifications

Background

The transcription factor NF-kappaB coordinates the activation of numerous genes in response to pathogens and pro-inflammatory cytokines, and is, therefore, vital in the development of acute and chronic inflammatory diseases. NF-kappaB is activated by cytokine-activated IKB kinases (IKKs) ; IKK-alpha and IKK-beta isozymes are found in large complexes These large, interleukin-1-inducible IKK complexes have been found to contain a new protein, termed IKK-complex-associated protein (IKAP), which can bind NIK and IKKs and assemble them into an active kinase complex. IKAP is a scaffold protein and a regulator for three different kinases involved in pro-inflammatory cytokine signaling.

Synonyms

Elongator complex protein 1, ELP1, DYS, IkappaB kinase complex associated protein, ikbkap, IKI3, p150, TOT1

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

ELP1

UniProt

O95163

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide corresponding to amino acids from the C-terminal region of human IKAP protein

Immunogen Type

Human

Target

IKAP

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

Format

Antigen Affinity Purified

Form

Liquid

Buffer

PBS + 0.02% NaN3

Shipping Conditions

Blue Ice

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.