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Anti-PTCH1 Antibody

Our PTCH1 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects mouse PTCH1 and is antigen affinity purified. It is great for use in WB.

Product Specifications

Background

Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with the nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas.

Synonyms

Patched, BCNS, Holoprosencephaly 7, HPE7, MES, NBCCS, PTCH protein, PTC

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Gene Name

PTCH1

UniProt

Q61115

Host

Rabbit

Reactivity

Mouse

Immunogen

Synthetic peptide corresponding to amino acids from mouse PTCH1 protein

Immunogen Type

Mouse

Target

PTCH1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Format

Antigen Affinity Purified

Form

Liquid

Buffer

PBS + 0.02% NaN3

Shipping Conditions

Blue Ice

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

WB Dilution

1:500-1:1000

Specificity

Reacts with mouse PTCH protein. Expected to cross react with rat, chicken and human due to 100% sequence identity.

Formulation

Prepared from pooled rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.

Quality Control

Western blots performed on each lot.

Species

Chicken, human, rat

Isotype

IgG

Curated Selection

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