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Anti-HERV Antibody

Our HERV rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human endogenous retrovirus (HERV) and is antigen affinity purified. It is great for use in WB.

Product Specifications

Background

HERVs are a class of multiple sclerosis associated retroviruses. Reacts with a replication competent Human Endogenous Retrovirus (HERVW) isolated from placenta. The synthetic peptide sequence used as immunogen is taken from the virus envelope polyprotein sequence. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. The HERVW endogenous envelope protein has retained its original fusogenic properties and participates in trophoblast fusion during placenta morphogenesis.

Synonyms

Human Endogenous Retrovirus, HERVW

Other Statements

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Host

Rabbit

Reactivity

Human Endogenous Retrovirus (HERV)

Immunogen

Synthetic peptide corresponding to amino acids from human Endogenous Retrovirus (HERV)

Immunogen Type

Human Endogenous Retrovirus

Target

HERV

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Format

Antigen Affinity Purified

Form

Liquid

Buffer

PBS + 0.02% NaN3

Shipping Conditions

Blue Ice

Storage Conditions

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

WB Dilution

1:500-1:1000

Specificity

Reacts with a replication-competent human Endogenous Retrovirus (HERV) isolated from placenta. HERVs are a class of multiple-sclerosis-associated retroviruses.

Formulation

Prepared from pooled rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.

Quality Control

Western blots performed on each lot.

Isotype

IgG

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