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Anti-TOMM20 Antibody

Our Anti-Mitochondrial Import Receptor Subunit TOM20 Homolog chicken polyclonal primary antibody from Aves Labs is produced in-house. It detects human, mouse, and rat TOMM20, and is affinity-purified IgY. It is great for use in ICC, IHC, WB.

Product Specifications

Background

TOMM20, or Translocase of Outer Mitochondrial Membrane 20, is a mitochondrial import receptor crucial for transporting proteins into the mitochondria, a process essential for energy production, metabolism, and apoptosis. Discovered in the 1990s as part of the TOM complex, TOMM20 binds precursor proteins and collaborates with other TOM components to channel them into the mitochondrion. This protein import sustains mitochondrial function and quality control, influencing mitochondrial dynamics like fusion and fission to meet cellular demands. Given its role in energy and metabolic regulation, TOMM20 dysfunction is linked to neurodegenerative disorders, including Parkinson’s (Di Maio et al. 2016) and Alzheimer’s (Pei et al. 2023), as well as certain cancers such as prostate (Yin et al.2023) and colorectal (Park et al 2019), making it a significant focus in research on mitochondrial-related diseases.

Short Description

Our Anti-We produce our Anti-TOMM20 Homolog chicken polyclonal primary antibody. It is great in ICC, IHC, WB and is affinity-purified IgY. no cross-reactivity reported human from Anti-TOMM20 Antibody is produced in-house. It is KO validated, detects We produce our Anti-TOMM20 Homolog chicken polyclonal primary antibody. It is great in ICC, IHC, WB and is affinity-purified IgY., and is 140. It is great for use in .

Synonyms

TOM20, MOM19, MAS20, Translocase Of Outer Mitochondrial Membrane 20 Homolog Type II, Mitochondrial Import Receptor Subunit TOM20 Homolog, Mitochondrial 20 KDa Outer Membrane Protein

Other Statements

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Gene Name

TOMM20

Host

Chicken

Reactivity

Human, Mouse, and Rat

Immunogen

Recombinant protein encompassing the full cytoplasmic domain of human TOMM20

Immunogen Type

Human

Target

Mitochondrial Import Receptor Subunit TOM20 Homolog

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ICC, IHC, WB

Field of Research

Cell Markers Mitochondrial Markers Mitochondrial Biology

Assay Protocol

Eggs from hens hyperimmunized with target were used to prepare an IgY fraction which was then subjected to antigen-specific affinity purification.

Concentration

200 µg/mL

Format

Affinity-Purified IgY

Buffer

Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline (“PBS, " pH 7.2) with sodium azide (0.02%, w/v) added as a preservative.

Molecular Weight

16 kDa

Shipping Conditions

Ice Packs

Storage Conditions

Store at 4°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile. For longer term storage, aliquot and freeze to avoid freeze-thaw of the antibody.

Specificity

No cross-reactivity reported

ICC Dilution

1:50-1:200

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used in Western blot.

Uniprot Accession Number

Q15388

Physical Properties

Liquid

Isotype

IgY

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