CD4 Antibody
Mouse monoclonal antibody to CD4
Product Specifications
Product Name Alternative
T4/Leu-3, L3T4
UniProt
P01730
Reactivity
Human
Immunogen
Human thymocytes and T lymphocytes.
Target
CD4
Clonality
Monoclonal
Clone
MEM-115
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Purified by protein-A affinity chromatography.
Concentration
1 mg/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Functional application: The antibody MEM-115 blocks binding of HIV gp120 to CD4 molecule and it also strongly inhibits CD4-MHC Class II interactions. Immunoprecipitation: Excellent. Flow cytometry: Recommended dilution: 3 μg/ml. Although it has not been tested rigorously, following data suggest that the antibody MEM-115 is a low-affinity antibody: its binding to T cells increases at elevated temperature, monovalent Fab fragments essentially do not bind to T cells.
Tested Applications
FA, FC, IP
Preservative
Phosphate buffered saline (PBS), pH 7.4
Isotype
Mouse IgG2a
Entrez
920
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