Cyclo (L-Phe-L-Pro)
Cyclo (L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide[1]. Cyclo (L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation[2]. Cyclo (L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC50 of 24 µM in the DPPH assay[3].
Product Specifications
CAS Number
[3705-26-8]
UNSPSC
12352209
Hazard Statement
H301, H311, H331
Target
Bacterial; Fungal; IFNAR; Reactive Oxygen Species (ROS)
Type
Peptides
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cyclo-l-phe-l-pro.html
Purity
99.91
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(N[C@H]1CC2=CC=CC=C2)[C@@](CCC3)([H])N3C1=O
Molecular Formula
C14H16N2O2
Molecular Weight
244.29
Precautions
H301, H311, H331
References & Citations
Lactobacillus plantarum
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
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