Cyclo (L-Phe-L-Pro)

Cyclo (L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide[1]. Cyclo (L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation[2]. Cyclo (L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC50 of 24 µM in the DPPH assay[3].

Product Specifications

CAS Number

[3705-26-8]

UNSPSC

12352209

Hazard Statement

H301, H311, H331

Target

Bacterial; Fungal; IFNAR; Reactive Oxygen Species (ROS)

Type

Peptides

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cyclo-l-phe-l-pro.html

Purity

99.91

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(N[C@H]1CC2=CC=CC=C2)[C@@](CCC3)([H])N3C1=O

Molecular Formula

C14H16N2O2

Molecular Weight

244.29

Precautions

H301, H311, H331

References & Citations

Lactobacillus plantarum

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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