Tyrphostin AG 1288
Tyrphostin AG 1288 is a potent Tyrosine Kinase inhibitor. Tyrphostin AG 1288 inhibits ICAM1 expression and TNFα-mediated cytotoxicity in vitro[1].
Product Specifications
CAS Number
116313-73-6
Product Name Alternative
AG 1288
UNSPSC
12352005
Target
C-Kit
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tyrphostin-ag-1288.html
Purity
98.68
Solubility
DMSO : ≥ 125 mg/mL
Smiles
N#C/C(C#N)=C/C1=CC([N+]([O-])=O)=C(O)C(O)=C1
Molecular Formula
C10H5N3O4
Molecular Weight
231.16
References & Citations
[1]Burke-Gaffney A, et al. Tumour necrosis factor-alpha-induced ICAM-1 expression in human vascular endothelial and lung epithelial cells: modulation by tyrosine kinase inhibitors. Br J Pharmacol. 1996 Nov;119 (6) :1149-58.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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