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Purified Anti-Mouse CD21/CD35 Antibody[7E9], Functional Grade

Product Specifications

Background

CD21, also known as CR2 (complement receptor 2) and C3d receptor, binds C3d and iC3b. It is also a receptor of Epstein-Barr virus. CD35, also known as CR1, binds C3b, iC3b, C4b, and iC4b. CD21/CD35 is primarily expressed on B lymphocytes, mast cells, follicular dendritic cells, macrophages, and activated granulocytes. CD21/CD35 forms part of the B-cell antigen receptor complex with CD19 and CD81 and is involved in signal transduction. None (Azide-Free, Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.

Abbreviation

CD35

Synonyms

Cr2

UniProt

P19070

Reactivity

Mouse

Immunogen

Recombinant Mouse CD21/CD35 protein

Clonality

Monoclonal

Clone

7000000000

Conjugation

None (AF/LE)

Applications

FCM; FA

Purification Method

>98%, Protein A/G purified

Concentration

≥ 3 mg/mL

Dilution

FCM ≤ 0.2 μg per million cells in 100 μL volume; FA Reported in the literature

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Host or Source

Rat

Control Catalog Number

E-AB-F098330

Isotype

Rat IgG2a, κ

Available Sizes

Frequently Asked Questions

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