Purified Anti-Mouse CD21/CD35 Antibody[7E9], Functional Grade
Product Specifications
Background
CD21, also known as CR2 (complement receptor 2) and C3d receptor, binds C3d and iC3b. It is also a receptor of Epstein-Barr virus. CD35, also known as CR1, binds C3b, iC3b, C4b, and iC4b. CD21/CD35 is primarily expressed on B lymphocytes, mast cells, follicular dendritic cells, macrophages, and activated granulocytes. CD21/CD35 forms part of the B-cell antigen receptor complex with CD19 and CD81 and is involved in signal transduction. None (Azide-Free, Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Abbreviation
CD35
Synonyms
Cr2
UniProt
P19070
Reactivity
Mouse
Immunogen
Recombinant Mouse CD21/CD35 protein
Clonality
Monoclonal
Clone
7000000000
Conjugation
None (AF/LE)
Applications
FCM; FA
Purification Method
>98%, Protein A/G purified
Concentration
≥ 3 mg/mL
Dilution
FCM ≤ 0.2 μg per million cells in 100 μL volume; FA Reported in the literature
Buffer
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Host or Source
Rat
Control Catalog Number
E-AB-F098330
Isotype
Rat IgG2a, κ
Available Sizes
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