BIO-013077-01
BIO-013077-01 is a pyrazole TGF-β inhibitor[1].
Product Specifications
CAS Number
746667-48-1
UNSPSC
12352005
Target
TGF-β Receptor
Type
Reference compound
Related Pathways
TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bio-013077-01.html
Purity
99.63
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=CC=CC(C2=NNC=C2C3=CC=C4N=CC=NC4=C3)=N1
Molecular Formula
C17H13N5
Molecular Weight
287.32
References & Citations
[1]Jin CH, et al. Synthesis and biological evaluation of 1-substituted-3 (5) - (6-methylpyridin-2-yl) -4- (quinoxalin-6-yl) pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors. Eur J Med Chem. 2011 Sep;46 (9) :3917-25.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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