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BIO-013077-01

BIO-013077-01 is a pyrazole TGF-β inhibitor[1].

Product Specifications

CAS Number

746667-48-1

UNSPSC

12352005

Target

TGF-β Receptor

Type

Reference compound

Related Pathways

TGF-beta/Smad

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bio-013077-01.html

Purity

99.63

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1=CC=CC(C2=NNC=C2C3=CC=C4N=CC=NC4=C3)=N1

Molecular Formula

C17H13N5

Molecular Weight

287.32

References & Citations

[1]Jin CH, et al. Synthesis and biological evaluation of 1-substituted-3 (5) - (6-methylpyridin-2-yl) -4- (quinoxalin-6-yl) pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors. Eur J Med Chem. 2011 Sep;46 (9) :3917-25.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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