Quinoline-2-carboxylic acid
Quinoline-2-carboxylic acid exhibits antidiabetic activity. Quinoline-2-carboxylic acid can be used as drug intermediate for synthesis of various active compounds[1][2].
Product Specifications
CAS Number
93-10-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Amylases; Glycosidase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/quinoline-2-carboxylic-acid.html
Concentration
10mM
Purity
99.99
Solubility
DMSO : ≥ 100 mg/mL|H2O : 50 mg/mL (ultrasonic)
Smiles
O=C(O)C1=NC(C=CC=C2)=C2C=C1
Molecular Formula
C10H7NO2
Molecular Weight
173.17
Precautions
H302, H315, H319, H335
References & Citations
[1]Lee H W, et al., Quinoline-2-carboxylic acid isolated from Ephedra pachyclada and its structural derivatives show inhibitory effects against α-glucosidase and α-amylase[J]. Journal of the Korean Society for Applied Biological Chemistry, 2014, 57: 441-444.|[2]Yang R, et al., Synthesis of Quinoline-2-Carboxylic Acid Aryl Ester and Its Apoptotic Action on PC3 Prostate Cancer Cell Line. Appl Biochem Biotechnol. 2023 Aug;195 (8) :4818-4831.|[3]Wade JJ, et al., Antiallergic activity of tetracyclic derivatives of quinoline-2-carboxylic acid. 2. Some benzothienoquinolinecarboxylic acids. J Med Chem. 1978 Sep;21 (9) :941-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
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