Quinoline-2-carboxylic acid

Quinoline-2-carboxylic acid exhibits antidiabetic activity. Quinoline-2-carboxylic acid can be used as drug intermediate for synthesis of various active compounds[1][2].

Product Specifications

CAS Number

[93-10-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Amylases; Glycosidase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/quinoline-2-carboxylic-acid.html

Concentration

10mM

Purity

99.99

Solubility

DMSO : ≥ 100 mg/mL|H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(O)C1=NC(C=CC=C2)=C2C=C1

Molecular Formula

C10H7NO2

Molecular Weight

173.17

Precautions

H302, H315, H319, H335

References & Citations

[1]Lee H W, et al., Quinoline-2-carboxylic acid isolated from Ephedra pachyclada and its structural derivatives show inhibitory effects against α-glucosidase and α-amylase[J]. Journal of the Korean Society for Applied Biological Chemistry, 2014, 57: 441-444.|[2]Yang R, et al., Synthesis of Quinoline-2-Carboxylic Acid Aryl Ester and Its Apoptotic Action on PC3 Prostate Cancer Cell Line. Appl Biochem Biotechnol. 2023 Aug;195 (8) :4818-4831.|[3]Wade JJ, et al., Antiallergic activity of tetracyclic derivatives of quinoline-2-carboxylic acid. 2. Some benzothienoquinolinecarboxylic acids. J Med Chem. 1978 Sep;21 (9) :941-8.