GMP Recombinant Human GH
Product Specifications
Background
Growth hormone (GH or GH-N) is also known as Somatotropin, Pituitary growth hormone. GH belongs to the somatotropin/prolactin family. Growth hormone (GH) may form monomer, dimer, trimer, tetramer and pentamer, by disulfide-linked or non-covalently associated, in homopolymeric and heteropolymeric combinations. GH can also form a complex either with GHBP or with the alpha2-macroglobulin complex. Growth hormone (GH) plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Product Name Alternative
GH1; Somatotropin; Growth hormone; GH; GH-N; Growth hormone 1; Pituitary growth hormone
Accession Number
P01241
Host
Mammalian cell
Target
GH
Tag
Tag free
Endotoxin
≤10 EU/mg
Purity
Greater than 95% as determined by reducing SDS-PAGE
Activity
Determined by its ability to stimulate the proliferation of Nb2-11 cells. Expected ED50 ≤ 0.1 ng/ml, corresponding to a specific Bioactivity of ≥ 1 x 10^ 7 units/mg
Form
Lyophilized
Buffer
10 mM PB, pH 7.4
Reconstitution
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Molecular Weight
22 kDa
Shipping Conditions
The product is shipped with ice bag. Upon receipt, store it immediately at the temperature listed below.
Storage Conditions
36 months at -20°C to -80°C in lyophilized state.6 months at -20°C to -80°C under sterile conditions after reconstitution.7-10 days at 2°C to 8°C under sterile conditions after reconstitution.Please minimize freeze-thaw cycles.
Construct
Recombinant Human GH is produced by our Mammalian cell expression system and the target gene encoding Phe27-Phe217 is expressed.
Species
Human
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