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GMP Recombinant Human GH

Product Specifications

Background

Growth hormone (GH or GH-N) is also known as Somatotropin, Pituitary growth hormone. GH belongs to the somatotropin/prolactin family. Growth hormone (GH) may form monomer, dimer, trimer, tetramer and pentamer, by disulfide-linked or non-covalently associated, in homopolymeric and heteropolymeric combinations. GH can also form a complex either with GHBP or with the alpha2-macroglobulin complex. Growth hormone (GH) plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.

Product Name Alternative

GH1; Somatotropin; Growth hormone; GH; GH-N; Growth hormone 1; Pituitary growth hormone

Accession Number

P01241

Host

Mammalian cell

Target

GH

Tag

Tag free

Endotoxin

≤10 EU/mg

Purity

Greater than 95% as determined by reducing SDS-PAGE

Activity

Determined by its ability to stimulate the proliferation of Nb2-11 cells. Expected ED50 ≤ 0.1 ng/ml, corresponding to a specific Bioactivity of ≥ 1 x 10^ 7 units/mg

Form

Lyophilized

Buffer

10 mM PB, pH 7.4

Reconstitution

Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Molecular Weight

22 kDa

Shipping Conditions

The product is shipped with ice bag. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

36 months at -20°C to -80°C in lyophilized state.6 months at -20°C to -80°C under sterile conditions after reconstitution.7-10 days at 2°C to 8°C under sterile conditions after reconstitution.Please minimize freeze-thaw cycles.

Construct

Recombinant Human GH is produced by our Mammalian cell expression system and the target gene encoding Phe27-Phe217 is expressed.

Species

Human

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