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GMP Recombinant Human Insulin

Product Specifications

Background

Insulin is a peptide hormone with 51 amino acids that plays a crucial role in regulating glucose homeostasis, cell growth, and metabolism . It is produced by the beta cells of the islets of Langerhans in the pancreas and is secreted in response to elevated blood glucose levels, such as after a meal . Insulin is synthesized as a prohormone called preproinsulin, which consists of 110 amino acids. This is processed to proinsulin, which includes the A-chain, B-chain, and C-peptide, and is then further processed to the active form of insulin with the removal of the C-peptide.

Product Name Alternative

Insulin; INS; IDDM; ILPR; IRDN; MODY10

Accession Number

P01308

Host

Yeast

Target

Insulin

Tag

Tag free

Endotoxin

≤10 EU/mg

Purity

Greater than 95% as determined by reducing SDS-PAGE

Form

Lyophilized

Buffer

Acetic acid

Reconstitution

Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Molecular Weight

6 kDa

Shipping Conditions

The product is shipped with ice bag. Upon receipt, store it immediately at the temperature listed below.

Storage Conditions

36 months at -20°C to -80°C in lyophilized state.6 months at -20°C to -80°C under sterile conditions after reconstitution.7-10 days at 2°C to 8°C under sterile conditions after reconstitution.Please minimize freeze-thaw cycles.

Construct

Recombinant Human Insulin is produced by our Yeast expression system and the target gene encoding αlpha chain: G-I-V-E-Q-C-C-T-S-I-C-S-L-Y-Q-L-E-N-Y-C-N & beta chain: F-V-N-Q-H-L-C-G-S-H-L-V-E-A-L-Y-L-V-C-G-E-R-G-F-F-Y-T-P-K-T is expressed.

Species

Human

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