RYK Mouse Monoclonal Antibody
Product Specifications
Background
May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C- terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
Product Name Alternative
Tyrosine-protein kinase RYK, 2.7.10.1, RYK, JTK5A
Gene Name
RYK
Gene ID
6259
Swiss Prot
P34925
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, FC
Field of Research
Wnt signaling pathway
Purification
Affinity Purification
Dilution
WB 1:500-1:2000, FC 1:25-1:50
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide.
Modification
Unmodified
Molecular Weight
67.8kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG1
Available Sizes
Curated Selection
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