MGMT Mouse Monoclonal Antibody

Product Specifications

Background

Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Product Name Alternative

Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase, MGMT

Gene Name

MGMT

Gene ID

4255

Swiss Prot

P16455

Host

Mouse

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, FC

Purification

Affinity Purification

Dilution

WB 1:1000-1:2000, FC 1:25-1:50

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide.

Modification

Unmodified

Molecular Weight

21.6kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

Mouse IgG1

Available Sizes

Curated Selection

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