HDAC2 Mouse Monoclonal Antibody
Product Specifications
Background
In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA.
Product Name Alternative
HDAC2; Histone deacetylase 2; HD2
Gene Name
HDAC2
Gene ID
3066
Swiss Prot
Q92769
Host
Mouse
Reactivity
Human, Mouse, Rat, Monkey
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, ICC
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, ICC 1:50-1:200
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 55 kDa; Observed MW: 60 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG2b
Available Sizes
Curated Selection
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