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TNFRSF11B Mouse Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Product Name Alternative

OPG; TR1; OCIF; MGC29565; TNFRSF11B

Gene Name

TNFRSF11B

Gene ID

4982

Swiss Prot

O00300

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

IHC, ELISA

Field of Research

Apoptosis

Purification

Affinity Purification

Dilution

IHC 1:200-1:1000, ELISA 1:5000-1:20000

Form

Liquid

Buffer

Ascitic fluid containing 0.03% sodium azide.

Modification

Unmodified

Molecular Weight

60kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

Mouse IgG1

Available Sizes

Curated Selection

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