TAB2 Mouse Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.
Product Name Alternative
CHTD2; FLJ21885; KIAA0733; MAP3K7IP2; TAB2
Gene Name
TAB2
Gene ID
23118
Swiss Prot
Q9NYJ8
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
ELISA, FC
Field of Research
MAPK signaling pathway
Purification
Affinity Purification
Dilution
ELISA 1:5000-1:20000, FC 1:200-1:400
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide.
Modification
Unmodified
Molecular Weight
80kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG1
Available Sizes
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