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KLHL1 Mouse Monoclonal Antibody

Product Specifications

Background

The mammalian Kelch like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin organizing proteins. Based on the presence of anti sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved in this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.Tissue specificity: Highly expressed in brain.

Product Name Alternative

MRP2; FLJ30047; KIAA1490; KLHL1

Gene Name

KLHL1

Gene ID

57626

Swiss Prot

Q9NR64

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

ICC, ELISA

Purification

Affinity Purification

Dilution

ICC 1:200-1:1000, ELISA 1:5000-1:20000

Form

Liquid

Buffer

Ascitic fluid containing 0.03% sodium azide.

Modification

Unmodified

Molecular Weight

82kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

Mouse IgG1

Available Sizes

Curated Selection

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