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HDAC4 Mouse Monoclonal Antibody

Product Specifications

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Product Name Alternative

HD4; HDACA; HA6116; HDAC-A; KIAA0288; HDAC4

Gene Name

HDAC4

Gene ID

9759

Swiss Prot

P56524

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, ELISA

Purification

Affinity Purification

Dilution

WB 1:500-1:2000, ELISA 1:5000-1:20000

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide

Modification

Unmodified

Molecular Weight

119kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

Mouse IgG1

Available Sizes

Curated Selection

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