CIB1 Mouse Monoclonal Antibody
Product Specifications
Background
CIB1 (also designated calcium and integrin binding 1 or calmyrin), with 191-amino acid protein (about 21kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha (IIb) beta (3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha (IIb) cytoplasmic domain of platelet integrin alpha (IIb) beta (3) . CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.
Product Name Alternative
CIB; KIP; KIP1; SIP2-28
Gene Name
CIB1
Gene ID
10519
Swiss Prot
Q99828
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ELISA
Field of Research
Apoptosis
Purification
Affinity Purification
Dilution
WB 1:500-1:2000, IHC 1:200-1:1000, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide.
Modification
Unmodified
Molecular Weight
21.7kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG1
Available Sizes
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