BLK Mouse Monoclonal Antibody
Product Specifications
Background
BLK (B lymphoid tyrosine kinase), with 505-amino acid protein (about 56KDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.
Product Name Alternative
MGC10442
Gene Name
BLK
Gene ID
640
Swiss Prot
P51451
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ELISA
Field of Research
Jak-STAT signaling pathway
Purification
Affinity Purification
Dilution
WB 1:500-1:2000, IHC 1:200-1:1000, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Ascitic fluid containing 0.03% sodium azide.
Modification
Unmodified
Molecular Weight
57.7kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Datasheet
https://assets.enkilife.com/files/monoclonal_antibody/AMM80554_EnkiLife_EN.pdf
Isotype
Mouse IgG1
Available Sizes
Curated Selection
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