JAK2 Mouse Monoclonal Antibody
Product Specifications
Background
Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2.
Product Name Alternative
JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2
Gene Name
JAK2
Gene ID
3717
Swiss Prot
O60674
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
PI3K-Akt signaling pathway, Jak-STAT signaling pathway
Purification
Affinity Purification
Dilution
IHC 1:50-1:100
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG1
Available Sizes
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