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FGF2 Mouse Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Product Name Alternative

BFGF; FGFB; FGF-2; HBGF-2

Gene Name

FGF2

Gene ID

2247

Swiss Prot

P09038

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

ELISA, FC

Field of Research

TGF-beta signaling pathway, PI3K-Akt signaling pathway, MAPK signaling pathway

Purification

Affinity Purification

Dilution

ELISA 1:5000-1:20000, FC 1:200-1:400

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide

Modification

Unmodified

Molecular Weight

30.8kd

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

Mouse IgG2a

Available Sizes

Curated Selection

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