CD192 Mouse Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3.
Product Name Alternative
CCR2; CKR2; CCR-2; CCR2A; CCR2B; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2
Gene Name
CD192
Gene ID
729230
Swiss Prot
P41597
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, ELISA, FC
Purification
Affinity Purification
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:20000, FC 1:200-1:400
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide
Modification
Unmodified
Molecular Weight
41.9kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG1
Available Sizes
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