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BLK Mouse Monoclonal Antibody

Product Specifications

Background

Blk is a Src family protein tyrosine kinase expressed in all stages of B cell development . Activation of B cells by various ligands is accompanied by activation of Blk . It has been suggested that Blk is involved in the control of B cell differentiation and proliferation . Blk transcripts have also been detected in human thymocytes, but not in mature T cells, implicating that Blk may play an important role in thymopoiesis . Blk function may be redundant, however, as mice that do not express Blk are not impaired with respect to B cell development and immune response .

Product Name Alternative

MODY11; MGC10442; BLK

Gene Name

BLK

Gene ID

640

Swiss Prot

P51451

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

ICC, ELISA, FC

Field of Research

Jak-STAT signaling pathway

Purification

Affinity Purification

Dilution

ICC 1:200-1:1000, ELISA 1:5000-1:20000, FC 1:200-1:400

Form

Liquid

Buffer

Ascitic fluid containing 0.03% sodium azide.

Modification

Unmodified

Molecular Weight

58kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

Mouse IgG1

Available Sizes

Frequently Asked Questions

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