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EphB6 Mouse Monoclonal Antibody

Product Specifications

Background

EPH receptor B6 (EphB6), with 1006-amino acid protein (~ 110 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Eph receptors and ephrin ligands are membrane-bound cell-cell communication molecules with well-defined functions in development. EphB6 is expressed both in a variety of embryonic and adult tissues. EphB6 is a unique member in the Eph family of receptor tyrosine kinases in that its kinase domain contains several alterations in conserved amino acids and is catalytically inactive. EphB6 can both positively and negatively regulate cell adhesion and migration and tyrosine phosphorylation of the receptor by an Src family kinase acts as the molecular switch for the functional transition.

Product Name Alternative

HEP; MGC129910; MGC129911

Gene Name

EphB6

Gene ID

2051

Swiss Prot

O15197

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ELISA

Purification

Affinity Purification

Dilution

WB 1:500-1:2000, IHC 1:200-1:1000, ELISA 1:5000-1:20000

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide

Modification

Unmodified

Molecular Weight

119kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Product Datasheet

https://assets.enkilife.com/files/monoclonal_antibody/AMM80538_EnkiLife_EN.pdf

Isotype

Mouse IgG1

Available Sizes

Curated Selection

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