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GRP78 BiP Mouse Monoclonal Antibody

Product Specifications

Background

When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) (PubMed 8020977) pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER) .

Product Name Alternative

HSPA5; GRP78; 78 kDa glucose-regulated protein; GRP-78; Endoplasmic reticulum lumenal Ca (2+) -binding protein grp78; Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein; BiP

Gene Name

GRP78 BiP

Gene ID

3309

Swiss Prot

P11021

Host

Mouse

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, ICC, IP

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, ICC 1:50-1:200, IP 1:10-1:20

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

Modification

Unmodified

Molecular Weight

Calculated MW: 72 kDa; Observed MW: 78 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

Mouse IgG2b

Available Sizes

Frequently Asked Questions

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