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Phospho-Histone H2A.X (Ser139) Mouse Monoclonal Antibody

Product Specifications

Background

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

Product Name Alternative

H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X; gamma H2A.X

Gene Name

Phospho-Histone H2A.X (Ser139)

Gene ID

3014

Swiss Prot

P16104

Host

Mouse

Reactivity

Human, Mouse

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, ICC

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, ICC 1:50-1:200

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

Modification

Phosphorylated

Molecular Weight

Calculated MW: 15 kDa; Observed MW: 15 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

Mouse IgG1

Available Sizes

Curated Selection

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