TNFRSF11A Mouse Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.
Product Name Alternative
FEO; OFE; ODFR; OSTS; PDB2; RANK; CD265; OPTB7; TRANCER; LOH18CR1; TRANCE-R
Gene Name
TNFRSF11A
Gene ID
8792
Swiss Prot
Q9Y6Q6
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, ELISA, FC
Purification
Affinity Purification
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:20000, FC 1:200-1:400
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide
Modification
Unmodified
Molecular Weight
66kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG1
Available Sizes
Curated Selection
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