CD127 Mouse Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a receptor for interleukin 7 (IL7) . The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V (D) J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID) . Alternatively spliced transcript variants have been found.
Product Name Alternative
IL7R; ILRA; IL7RA; CDW127; IL-7R-alpha
Gene Name
CD127
Gene ID
3575
Swiss Prot
P16871
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, ELISA, FC
Field of Research
TGF-beta signaling pathway, PI3K-Akt signaling pathway, Jak-STAT signaling pathway
Purification
Affinity Purification
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:20000, FC 1:200-1:400
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide
Modification
Unmodified
Molecular Weight
51.6kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG2b
Available Sizes
Curated Selection
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