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TNFRSF11A Mouse Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.

Product Name Alternative

FEO; OFE; ODFR; OSTS; PDB2; RANK; CD265; OPTB7; TRANCER; LOH18CR1

Gene Name

TNFRSF11A

Gene ID

8792

Swiss Prot

Q9Y6Q6

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

ELISA, FC

Purification

Affinity Purification

Dilution

ELISA 1:5000-1:20000, FC 1:200-1:400

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide

Modification

Unmodified

Molecular Weight

66kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

Mouse IgG1

Available Sizes

Frequently Asked Questions

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