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RUNX3 Mouse Monoclonal Antibody

Product Specifications

Background

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Product Name Alternative

AML2; CBFA3; PEBP2aC; FLJ34510; MGC16070

Gene Name

RUNX3

Gene ID

864

Swiss Prot

Q13761

Host

Mouse

Reactivity

Human, Mouse

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

IHC, ICC, ELISA, FC

Purification

Affinity Purification

Dilution

IHC 1:200-1:1000, ICC 1:200-1:1000, ELISA 1:5000-1:20000, FC 1:200-1:400

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide

Modification

Unmodified

Molecular Weight

44.4kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

Mouse IgG2b

Available Sizes

Curated Selection

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