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RUNX1 Mouse Monoclonal Antibody

Product Specifications

Background

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.

Product Name Alternative

AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; AML1-EVI-1; RUNX1

Gene Name

RUNX1

Gene ID

861

Swiss Prot

Q01196

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, ICC, ELISA

Purification

Affinity Purification

Dilution

WB 1:500-1:2000, ICC 1:200-1:1000, ELISA 1:5000-1:20000

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide.

Modification

Unmodified

Molecular Weight

55kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

Mouse IgG1

Available Sizes

Frequently Asked Questions

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