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AURKA Mouse Monoclonal Antibody

Product Specifications

Background

Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.

Product Name Alternative

AIK; ARK1; AURA; BTAK; STK6; STK7; STK15; AURORA2; MGC34538; AURKA

Gene Name

AURKA

Gene ID

6790

Swiss Prot

O14965

Host

Mouse

Reactivity

Human, Rat, Monkey

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ELISA

Purification

Affinity Purification

Dilution

WB 1:500-1:2000, IHC 1:200-1:1000, ELISA 1:5000-1:20000

Form

Liquid

Buffer

Ascitic fluid containing 0.03% sodium azide.

Modification

Unmodified

Molecular Weight

48kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

Mouse IgG1

Available Sizes

Curated Selection

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