Proteinase 3 Mouse Monoclonal Antibody
Product Specifications
Background
Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
Product Name Alternative
PRTN3; ACPA; CANCA
Gene Name
Proteinase 3
Gene ID
5657
Swiss Prot
P24158
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
ICC, ELISA, FC
Purification
Affinity Purification
Dilution
ICC 1:50-1:200, ELISA 1:5000-1:20000, FC 1:200-1:400
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide.
Modification
Unmodified
Molecular Weight
28kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG2b
Available Sizes
Curated Selection
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