PI3 Kinase p85 alpha Mouse Monoclonal Antibody
Product Specifications
Background
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
Product Name Alternative
PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha
Gene Name
PI3 Kinase p85 alpha
Gene ID
5295
Swiss Prot
P27986
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC
Field of Research
TGF-beta signaling pathway, PI3K-Akt signaling pathway, Jak-STAT signaling pathway
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IHC 1:50-1:100
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 84 kDa; Observed MW: 84 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG1
Available Sizes
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