EGFR Mouse Monoclonal Antibody
Product Specifications
Background
EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.
Product Name Alternative
EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
Gene Name
EGFR
Gene ID
1956
Swiss Prot
P00533
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC
Field of Research
TGF-beta signaling pathway, PI3K-Akt signaling pathway, MAPK signaling pathway, Jak-STAT signaling pathway, Hippo signaling pathway
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, ICC 1:50-1:200
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 134 kDa; Observed MW: 170 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG1
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
D3206-98-AP 200 µL
DERL2, CT (Derlin-2, Der1-like Protein 2, Degradation In Endoplasmic Reticulum Protein 2, DERtrin-2, F-LAN-1, F-LANa, SBBI53, CGI-101, FLANA, DER2) (AP) discontinued
Ask
View Details 
![Mouse Monoclonal Canine Parvovirus Antibody (8H7) [Alexa Fluor 532]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
NB100-73204AF532 0.2 mL
Mouse Monoclonal Canine Parvovirus Antibody (8H7) [Alexa Fluor 532]
Ask
View Details 