SMAD5 Mouse Monoclonal Antibody
Product Specifications
Background
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD) . SMAD5 is required for normal development of the cardiovascular system in vivo; lack of the SMAD5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of SMAD5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous.
Product Name Alternative
Dwfc; JV5-1; MADH5; DKFZp781C1895; DKFZp781O1323; SMAD5
Gene Name
SMAD5
Gene ID
4090
Swiss Prot
Q99717
Host
Mouse
Reactivity
Human, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC, ELISA, FC
Field of Research
TGF-beta signaling pathway
Purification
Affinity Purification
Dilution
WB 1:500-1:2000, IHC 1:200-1:1000, ICC 1:200-1:1000, ELISA 1:5000-1:20000, FC 1:200-1:400
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide.
Modification
Unmodified
Molecular Weight
52kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG1
Available Sizes
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