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H2AFX Mouse Monoclonal Antibody

Product Specifications

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Product Name Alternative

H2AX; H2A.X; H2A/X

Gene Name

H2AFX

Gene ID

3014

Swiss Prot

P16104

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC, FC

Purification

Affinity Purification

Dilution

WB 1:500-1:2000, IHC 1:200-1:1000, ICC 1:50-1:200, FC 1:200-1:400

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide

Modification

Unmodified

Molecular Weight

15.1kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

Mouse IgG1

Available Sizes

Curated Selection

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